- Does it elicit a psychoactive reaction or does it affect TRPV3 in vitro? - be honest David Beckham meme - In vivo in mice 
- is TRPV3 even involved in any way because last time i’ve checked some of best evidence points in direction of TrkB 
 
- I got some frankincense and lit it, now my apartment smells like smoke - Just as John Frankincense intended. 
 
- I want to see someone correct that commentor by telling them frankincense was the name of the doctor not the monster. - Frankincense was actually the name of the wise man. - Knowledge is knowing Frankincense is the doctor. Wisdom is knowing Frankincense is the monster - Frankly, that makes no sense 
 
 
- The monster’s name was Adam Frankincense. 
 
- incensole acetate has ~1/10th the anti-anxiety potency of valium, which is pretty darn high if you think about it! - myrrh is also psychoactive, but it’s a straight up opoid agonist. it was commonly used as a pain reliever before the widespread use of opium poppies. in high-ish concentrations folks report general euphorua, dream-like states, and even vivid/lucid dreams! i can personally attest to the first two hahah - Next you’re gonna tell me gold is psychoactive! - Having lots of it would indeed make me happier :p 
 
 
- Now someone is going to make a Frankincense vapes - Extract in a passive nasal inhaler device like Poy-Sian would probably work.  - Is that bottle actually labeled “Poy-sian” like poison? - Its from Thailand… There is a stop between the word and a heavy emphasis on the y. - Phoentically It’s like poY - - see - an 
 
 
 
- So, uh, how would one make use of this knowledge? - Probably shouldn’t experiment with large doses of barely understood substances… But if someone really wanted to. - You can buy Incensole Acetate from chemical companies, but it’s like hundred dollars for a few milligrams. Would have been cool for it to be cheap this form because you could probably use it in a passive nasal inhaler device at that strength. - However you can buy 4oz of frankincense resin for ~$30. I would imagine that will have much more of Incensole than a few mg. No idea if it would be easy to inhale in vapor form or if you would have to burn it. - No idea how reputable these sites selling it are, but here is one. - How have we allowed a substance used by a major religion for two millennia remain a “barely understood substance?” - Yeah, but they weren’t inhaling an isolate. It’s all about the dose. - Edit: I misread your comment. I don’t know why there isn’t more research into the pathways frankincense uses to generate its effects. Probably because it’s rarely been used in a directly applied medical way instead of a communal or ceremonial use. 
 
 
 
- Religion itself is said to be natural antidepressant. I do wonder if exposure by our ancestors to psychoactive substances is tied to the development of religion. - Hell just the chords they play on the organ. You could probably write a song about licking envelopes in the style of a church hymn and get people to worship the Postmaster General. - I mean, I have been looking for a cult to join, if you were looking to start one. - Well join us at !woodworking@lemmy.ca. We could use a wood scientist. 
 
 
 
- Uh yeah, how is that new? That was always the point of using the stuff. - I figured it was traditionally used because it’s what was given to baby JC by the three wise men, so it’s considered holy in a sense - It’s a drug and has always been used as such. Why do you think that stuff was so valuable? - Smells nice? I mean, that’s basically the value of perfumes too 
- Bcs the market speculation predicted that after prob 1k years it will enter the mass use by a major religion & could be sold at a higher price then, duh. - /s 
 
 
 
- Here and I thought the smoke was meant to keep mosquitos away - Maybe it doesn’t actually keep them away but just gets them too high to be interested in biting. - But the higher I get, the more interested in biting I become 
 
 
- I actually got my hands on Frankincense drops and started to eat them like crazy, when I decided to try one of them. It tasted like actual raw glass like rocks although I liked eating them and didn’t knew why until now. Although they have almost zero to non taste, eating them was quite addictive in my experience 
- That’s what they used to call “Church Air” 
- So the Church has wine and antidepressants in its rituals… 
- Somewhere, Dr. Ammon Hillman has read this and is grinning maniacally. - I was going to go with Marx. Turns out religion is the LITERAL opiate of the masses! - Makes sense with Marx too I guess but Hillman, who has a doctorate in classics and a masters (I think) in one of the biosciences has been pushing for more awareness of the countless references to recreational and sacramental drug use in antiquity for over a decade now. He’s not for everybody but he’s read ancient Greek for over 3 decades and finds some pretty surprising accounts of it in neglected medical and other texts he continues to translate. 
 
 
- I’ll stick with my family trait that means when we fight we get happy brain juice, I just wish boxing or MMA could trigger it but it doesn’t. If the fight can’t theoretically end with me getting gutted with a rusty knife I want nothing to do with it, I want to Cain someone’s Able. - Okay? Stay safe, I guess - Eh I generally have to avoid activating that particular trait, it’s rather unproductive. Also I shit talk a lot while in a fight and that could get me in deeper water due to fighting words laws. - In Washington State, we have mutual combat laws! So long as both parties agree to fight and not hurt anyone else or other’s property, you are good to fight! - How the fuck did you guys retain dueling laws? 
 
 
 
 












